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Three nanobodies (blue) are shown bound to the tip of the SARS-CoV-2 spike protein (red/pink). The nanobodies were engineered to be extremely effective at blocking the virus from entering a host cell. (Credit: UCSF) An amazing new material called an avalanching nanoparticle, which was co-developed by researchers in Berkeley Lab’s Molecular Foundry, is featured in a cover story of the Jan. 14 edition of the world-renowned scientific journal Nature. A ribbon diagram rendering of the ORF8 structure predicted by AlphaFold 2 (blue), overlaid onto the actual structure (green) determined by the UC Berkeley-led team. (Credit: DeepMind) Soft X-ray tomography provides a map of organelles within an intact cell. (Credit: Katya Kadyshevskaya/USC) Artistic interpretation of CheckV assessing virus genome sequences from environmental samples. (Rendered by Zosia Rostomian​, Berkeley Lab) Unicellular algae in the Chlorella genus, magnified 1300x. (Andrei Savitsky) Collage of partial Bragg spots recorded during experiments at the XFEL. For each pixel in the `shoe-box' of a given Bragg spot, diffBragg applies precise modelling of the various parameters affecting their shape and intensity. An artistic rendering of phages. (Credit: Antara Mutalik)

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