Maize (Zea mays) produces a plethora of antibiotics called zealexins. These compounds protect maize by fending off fungal and microbial infections. Scientists had assumed that maize synthesizes these compounds via clear, straight pathways, entailing the function of more than a dozen enzymes. But now, with the help of JGI’s DNA synthesis capability, researchers know that just a handful of enzymes are needed to transform zealexins and related precursors into a bonanza of diverse structures. Read more of the science highlight on the JGI website.
Three from Biosciences Area Named AAAS Fellows
The American Association for the Advancement of Science (AAAS), which was founded in 1848 and is the world’s largest general scientific society, announced that 489 of its members—among them nine scientists at Berkeley Lab—have been named Fellows. This lifetime honor, which follows a nomination and review process, recognizes scientists, engineers, and innovators for their distinguished achievements toward the advancement or applications of science.
The three newly named Fellows from the Biosciences Area are: Sanjay Kumar, a faculty scientist in the Biological Systems and Engineering (BSE) Division; Mary Maxon, the Associate Laboratory Director for the Biosciences Area; and Len Pennacchio, a senior scientist in the Environmental Genomics and Systems Biology (EGSB) Division and the Deputy of Genomic Technologies at the DOE Joint Genome Institute (JGI).
Video Chosen for Global Bioeconomy Summit 2020
The Biosciences Area coordinated the production of a video, “Supporting the US Bioeconomy: The Role of the DOE National Laboratories,” which was the only video submitted from the United States for inclusion in the Global Bioeconomy Summit 2020.
How to Reduce Greenhouse Gas? Tips from a Methane-Eating Microbe
Scientists have determined the structure of a unique enzyme, produced by a species of methane-eating bacteria, that converts the greenhouse gas into methanol – a highly versatile liquid fuel and industrial product ingredient.
Their new study, published in the Journal of the American Chemical Society, is the first to report the structure of the enzyme, called soluble methane monooxygenase (sMMO), at room temperature in both its reduced and oxidized forms. This detailed structural information will help researchers design efficient catalysts for industrial methane to methanol conversion processes.
David Schaffer Named Acrivos Professional Progress Award Recipient
The Andreas Acrivos Award for Professional Progress in Chemical Engineering is endowed by the AIChE Foundation in the name of fluid-dynamics pioneer Andreas Acrivos of the City College of New York. The prize recognizes outstanding progress in chemical engineering by a member of AIChE in their early career. The recipient of the 2020 Professional Progress Award is David Schaffer, a faculty scientist in Molecular Biophysics and Integrated Bioimaging (MBIB), as well as a professor of chemical and biomolecular engineering at UC Berkeley, where he also directs the California Institute for Quantitative Biosciences. Schaffer was recognized for implementing molecular and cellular engineering strategies to overcome challenges in the development of gene and cell therapies. In particular, he developed the concept of applying directed evolution to engineer targeted and efficient viral gene therapy vectors, which led to novel adeno-associated viral vectors being used in multiple human clinical trials. In addition, he has developed new technologies to investigate and control stem cell fate decisions. Read more from AIChE.
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