As part of Berkeley Lab’s 90th Anniversary, we’re reflecting back in history on all that has been accomplished in biological sciences; talking in the present with Associate Laboratory Director for Biosciences, Mary Maxon; and looking forward to the future with project scientist Nathalie Elisabeth in the Molecular Biophysics and Integrated Bioimaging (MBIB) Division.
Mary Maxon Writes About Bioengineering for the Future
Mary Maxon, Associate Lab Director for Biosciences, co-wrote the cover story for the March/April 2021 edition of The Environmental Law Institute’s (ELI) policy magazine, The Environmental Forum. Maxon and her co-author, David Rejeski, a visiting scholar at ELI, discussed everything related to the bioeconomy: economic activity that is driven by research and innovation in the life sciences and biotechnology, and that is enabled by technological advances in engineering and in computing and information sciences.
New Protein Functions from Beneficial Human Gut Bacterium
Researchers in the Environmental Genomics and Systems Biology (EGSB) and Biological Systems and Engineering (BSE) Divisions at Berkeley Lab employed a large-scale functional genomics approach to systematically characterize Bacteroides thetaiotaomicron, a beneficial bacterium prevalent in the human gut. They performed hundreds of genome-wide fitness assays and identified new functions for 40 proteins, including antibiotic tolerance, polysaccharide degradation, and colonization of the GI tract in germ-free mice.
Solving a Genetic Mystery at the Heart of the COVID-19 Pandemic
As the COVID-19 pandemic enters its second year, scientists are still working to understand how the SARS-CoV-2 strain evolved, and how it became so much more dangerous than other coronaviruses, which humans have been living alongside for millennia. Virologists and epidemiologists worldwide have speculated for months that a protein called ORF8 likely holds the answer, and a recent study by Berkeley Lab scientists has helped confirm this hypothesis.
Location, Location, Location: Regional Tau Deposits in Healthy Elders Predict Alzheimer Disease
Xi Chen and her colleagues in Bill Jagust’s research group at Berkeley Lab recently published a study in the Journal of Neuroscience that provides some clarification of the differences between normal aging and AD brains, and elucidates the transition from the former to the latter.
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