Using physical chemistry methods to look at biology at the nanoscale, faculty scientist Ke Xu has invented a new technology to image single molecules with unprecedented spectral and spatial resolution, enabling new ways to examine cell structures and study diseases like Alzheimer’s. Xu, of the Molecular Biology & Integrated Bioimaging Division, has dubbed his innovation SR-STORM, or spectrally resolved stochastic optical reconstruction microscopy. Because SR-STORM gives full spectral and spatial information for each molecule, the technology opens the door to high-resolution imaging of multiple components and local chemical environments, such as pH variations, inside a cell. Read more at the Berkeley Lab News Center.
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