Karen Davies
Biophysicist Staff Scientist
Molecular Biophysics and Integrated Bioimaging
- Structural Biology
Building: 1, Room 312
Mail Stop: DONNER
Phone: (510) 486-4466
Fax: Fax: (510) 486-6488
[email protected]
Research Interests
- Protein structure
- Bioenergetic membranes
- Cellular organisation
- Electron cryo tomography
Using electron cryo-tomography with sub-tomogram averaging together with single particle electron cryo-microscopy, we aim to determining how the structure and organization of proteins in situ influence cellular structure and function. My lab focuses on understanding the biogenesis of bioenergetic compartments and how the structure of these compartments changes with changing environmental conditions such as light, temperature and nutrient availability.
Current projects:
- Role of ATP synthase in shaping mitochondrial cristae
- Role of NADH and NADPH dehydrogenases in carbon fixation
- Assembly of carboxysomes
Microscope equipment:
- Jeol 3100 with in column energy filter and K2 camera
- Titan with K2 camera
- Philips/FEI CM200F with 2K CCD
- JEOL-1200
- 2 Vitrobots
- Cryo-microtome
- Microtome
